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Drug & Alcohol Rehab Centers in Santa Ana, California

Discover 15 addiction treatment facilities in Santa Ana. Our comprehensive directory helps you find the right rehabilitation center with 24/7 support available, licensed facilities, and insurance accepted at most locations. Whether you need detox services, residential treatment, outpatient programs, or sober living arrangements, find the perfect match for your recovery journey.

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Showing 15 of 15 results

Cornerstone Adult Outpatient
+9 photos
1950 East 17th Street, 92705
714-547-4300
Cornerstone Adult Outpatient in Santa Ana provides comprehensive substance use disorder treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and contingency management. Specializing in co-occurring mental health and pain conditions, the facility offers flexible care levels from intensive outpatient programs to methadone and buprenorphine treatment. Accredited by The Joint Commission and state health authorities, Cornerstone serves active duty military, criminal justice clients, and adults seeking recovery with telehealth options available.
Substance use treatment
Newport Academy
+9 photos
9951 Highcliff Drive, 92705
877-820-6371
Newport Academy in Santa Ana, CA specializes in comprehensive substance use treatment and co-occurring mental health disorders for adolescents and adults. The facility offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling across multiple treatment settings from intensive outpatient to residential care. Accredited by The Joint Commission and the State Department of Health, Newport Academy provides culturally competent care with specialized support for LGBTQ clients and trauma survivors.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
12822 Periwinkle Drive, 92705
855-272-7451
Newport Institute in Santa Ana, CA specializes in comprehensive substance use treatment and co-occurring mental health care for both adults and children. The facility offers evidence-based approaches including cognitive behavioral therapy, trauma counseling, and relapse prevention across multiple treatment settings—from intensive outpatient to 24-hour residential care. With Joint Commission accreditation and state health department certification, Newport Institute is recognized for its integrated approach to treating complex cases where substance use and serious mental illness intersect.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
9881 Deerhaven Drive, 92705
855-272-7451
Newport Institute in Santa Ana, CA specializes in comprehensive substance use and co-occurring mental health treatment for both adults and adolescents. The facility offers multiple levels of care from intensive outpatient programs to 24-hour residential treatment, utilizing evidence-based approaches including cognitive behavioral therapy, trauma-informed care, and relapse prevention. Known for its inclusive, affirming environment and Joint Commission accreditation, Newport Institute serves individuals navigating complex dual diagnoses with compassionate, personalized treatment pathways.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
10022 Miramar Circle, 92705
855-272-7451
Newport Institute in Santa Ana, CA provides comprehensive substance use treatment with specialized care for co-occurring mental health conditions in adults and emotional disturbances in children. The facility offers flexible treatment settings ranging from intensive outpatient programs to long-term residential care, utilizing evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling. State-licensed and Joint Commission accredited, Newport Institute delivers personalized recovery pathways for individuals and families seeking sustainable healing.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Pacific Sands Recovery Center
+9 photos
1909 West Carlton Place, 92704
844-568-7328
Pacific Sands Recovery Center in Santa Ana, CA provides comprehensive detoxification and substance use treatment for adults with co-occurring mental health conditions. The center offers both hospital inpatient and residential detoxification options, utilizing evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. Accredited by The Joint Commission and state health agencies, the facility specializes in serving diverse populations including veterans, LGBTQ individuals, trauma survivors, and those managing co-occurring pain and substance use disorders.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Phoenix House
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Phoenix House

Orange County

1207 East Fruit Street, 92701
714-953-9373
Phoenix House in Santa Ana provides comprehensive detoxification and substance use treatment with specialized care for co-occurring mental health and emotional challenges. Their integrated approach combines evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling across multiple care settings from intensive outpatient to residential programs. With CARF, Joint Commission, and multiple state accreditations, this facility serves diverse populations including LGBTQ individuals, veterans, and those with complex medical needs.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Recovery Homes of America Inc
+9 photos
1950 East 17th Street, 92705
714-567-5345
Recovery Homes of America Inc in Santa Ana, CA specializes in comprehensive substance use treatment with evidence-based approaches including CBT, motivational interviewing, and relapse prevention. The facility serves diverse populations including active duty military, individuals with co-occurring mental health and pain conditions, and those involved in the criminal justice system. Their flexible treatment options range from intensive outpatient programs to medication-assisted therapy, all delivered with Joint Commission accreditation standards.
Substance use treatment
Santa Ana Comprehensive Treatment Ctr
+9 photos
Santa Ana Comprehensive Treatment Ctr

California Treatment Services LLC

2101 East 1st Street, 92705
714-581-9181
Santa Ana Comprehensive Treatment Center in Santa Ana, CA delivers integrated detoxification and substance use disorder treatment through evidence-based outpatient programs. Specializing in medication-assisted treatment (methadone, buprenorphine, naltrexone) alongside behavioral therapies, the center serves diverse populations including veterans, LGBTQ+ individuals, trauma survivors, and those with co-occurring mental health or pain conditions. CARF-accredited and SAMHSA-certified, it provides accessible care designed for sustained recovery.
DetoxificationSubstance use treatment
Orange County Healthcare Agency
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Orange County Healthcare Agency

Behavioral Health Services/SUD

401 West Civic Center Drive, 92701
714-834-3840
Orange County Healthcare Agency in Santa Ana provides comprehensive substance use disorder treatment with evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and relapse prevention. Specializing in trauma-informed care, the agency serves diverse populations including pregnant and postpartum women, adult men and women, and individuals with co-occurring mental health conditions. Their flexible service model spans intensive outpatient, regular outpatient, and medication-assisted treatment options with telemedicine availability.
Substance use treatment
Orange County Healthcare Agency
+4 photos
Orange County Healthcare Agency

Drug Court and DUI Programs

401 West Civic Center Drive, 92701
714-480-6650
Orange County Healthcare Agency in Santa Ana provides comprehensive substance use treatment through evidence-based outpatient programs and medication-assisted therapy. Their specialized team delivers cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling alongside relapse prevention strategies. As a state-accredited substance use treatment agency, they offer flexible care options including intensive outpatient, telehealth services, and medication management with methadone, buprenorphine, or naltrexone.
Substance use treatment
PES/EBS Inc
600 West Santa Ana Boulevard, 92701
530-888-1010
PES/EBS Inc in Santa Ana provides comprehensive substance use treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. The facility serves individuals involved in the criminal justice system with flexible outpatient options, including intensive programs and medication-assisted treatment with methadone, buprenorphine, or naltrexone. State-accredited and experienced with forensic populations, they tailor treatment intensity to meet each client's unique recovery needs.
Substance use treatment
Cooper Fellowship Inc - Placeholder
409 North Cooper Street, 92703
714-554-1152
Cooper Fellowship Inc in Santa Ana, CA provides comprehensive substance use treatment through long-term residential care, serving diverse populations including veterans, military families, and individuals with trauma histories. The facility specializes in evidence-based approaches such as cognitive behavioral therapy, trauma-related counseling, and the Matrix Model, with dedicated support for clients experiencing co-occurring mental health disorders, pain conditions, and intimate partner violence. Their specialized programs address the unique needs of LGBTQ individuals, active duty military, and those involved in the criminal justice system.
Substance use treatment
Straight Talk Clinics Inc - Placeholder
1225 West 6th Street, 92703
714-972-1402
Straight Talk Clinics Inc in Santa Ana provides comprehensive substance use treatment with both residential and telehealth options, serving diverse populations including LGBTQ+ individuals, veterans, trauma survivors, and those with co-occurring disorders. The facility specializes in evidence-based approaches like cognitive behavioral therapy, motivational interviewing, and the Matrix Model, alongside trauma-informed care and support for clients with HIV/AIDS. Accredited by the State Substance Use Treatment Agency and State Department of Health, Straight Talk combines clinical expertise with culturally competent services for lasting recovery.
Substance use treatment
Villa Center Inc - Placeholder
910 North French Street, 92701
714-541-2732
Villa Center Inc in Santa Ana, CA specializes in comprehensive substance use treatment through short-term, residential, and long-term residential programs. The facility offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, trauma-focused counseling, and relapse prevention, with particular expertise serving military families, veterans, LGBTQ individuals, and survivors of intimate partner violence and sexual abuse. Villa Center's multi-disciplinary team addresses co-occurring mental health and substance use disorders with compassionate, trauma-informed care.
Substance use treatment

Addiction Treatment in Santa Ana

Santa Ana is home to a diverse range of addiction treatment facilities, offering comprehensive care for individuals struggling with substance abuse and co-occurring mental health disorders. Whether you're a resident of Santa Ana or traveling for treatment, you'll find quality rehabilitation centers that can help you begin your recovery journey.

Why Choose Treatment in Santa Ana?

  • • Accessibility: Multiple treatment centers throughout the city with various specializations
  • • Quality Care: Licensed and accredited facilities with experienced professionals
  • • Diverse Options: From luxury rehabs to affordable state-funded programs
  • • Support Network: Strong recovery community with numerous support groups
  • • Continuum of Care: Full spectrum from detox to aftercare services

Types of Programs Available

Treatment centers in Santa Ana offer various levels of care to meet different needs:

  • • Medical Detox: Safe, supervised withdrawal management
  • • Inpatient/Residential: 24/7 care in a structured environment
  • • Partial Hospitalization (PHP): Intensive day treatment programs
  • • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • • Standard Outpatient: Weekly therapy and support groups
  • • Sober Living: Transitional housing for ongoing recovery support

Getting Started with Treatment

Finding the right treatment center in Santa Ana starts with understanding your specific needs. Consider factors such as the type of substance use, any co-occurring mental health conditions, insurance coverage, and personal preferences for treatment approach. Many facilities offer free consultations to help you determine the right fit for your recovery journey.